Factory Supply Pirfenidone(S-7701,AMR-69) 99% CAS NO.53179-13-8

1.We set up R&D lab in Wuhan,customize service is available.
2.We have two factories in Dezhou , Shandong and Xianning, Hubei. The factory covers an area of 48,000 square meters with the building area of 26,000 square meters
3.We passed ISO quality system certificates
4. We have6 patents passed the preliminary examination, and 4 patents are under examination and approval.

Pirfenidone

CAS:

53179-13-8

MF:

C12H11NO

MW:

185.22

EINECS:

621-260-7

Properties

Melting point:

96-97°C

Boiling point:

329.1±15.0 °C(Predicted)

Density 

1.137±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO: ≥10 mg/mL, soluble

form 

solid

pka

-0.16±0.63(Predicted)

color 

Off-white

Application:Pirfenidone is a broad-spectrum antifibrotic drug that modulates diverse cytokine action involving TGF-β, TNF-α, epidermal growth factor, platelet-derived growth factor,vascular endothelial growth factor, insulin-like growth factor 1, fibroblast growth factor, and others.Pirfenidone has been effective in the prevention and regression of pulmonary fibrosis, peritoneal sclerosis, hepatic cirrhosis, uterine fibromyoma, and other scarring and fibrotic conditions. It doesn’t cure the condition or reverse any existing scarring but it can effectively slow down the rate of lung function decline by about 50%. In the UK, Pirfenidone is currently only approved for treating IPF, and not for other forms of pulmonary fibrosis.